1. Top Destinations
  2. Panama
  3. Eastern Panama
  4. Tours & Sightseeing

Eastern Panama Tours & Sightseeing: Your Guide to Art, Nature, and Cultural Experiences with Varoom

In Eastern Panama, Panama, you’ll discover iconic experiences like island-hopping in the San Blas Islands with its vibrant Guna Yala culture, coastal snorkeling, and dhow-style boat trips. Explore the historic allure of Portobelo in Colon, plus immersive treks through Darien National Park for wildlife and jungle adventures, all conveniently connected to stays that suit your event-filled itinerary.

Discover Eastern Panama, Panama and let this destination unfold with river safaris, lush rainforests, and inviting beaches. In this region you’ll find adventures from wildlife-watching tours and waterfall hikes to sailing along the Caribbean coast and exploring Indigenous culture and vibrant markets. Here, you can book experiences across Art & Culture, Adventure & Thrill, and Tours & Sightseeing, from multi-day explorations to family-friendly activities, all tailored to your plans with Varoom. The area offers immersive experiences, Nature & Wildlife encounters, and wellness retreats that pair well with comfortable stays and easy transportation to landmarks and POIs nearby. Use this destination to discover popular experiences, landmarks, and things to do, and let your trip align with the Events you’re seeking to host or attend.

Activities

Top Tours & Sightseeing in Eastern Panama

Small-Group Beach Day Trip from Panama City to Isla Grande
Small-Group Beach Day Trip from Panama City to Isla Grande
10
Excellent
1 Reviews
5-Star Rating Recommendation
From
US $165Per Person
Reserve
San Blas Money Heist Island Day tour - 2-islands + Natural Pool
San Blas Money Heist Island Day tour - 2-islands + Natural Pool
10
Excellent
6 Reviews
5-Star Rating Recommendation
From
US $76Per Person
Reserve
San Blas Full-Day Group Tour from Panama City
San Blas Full-Day Group Tour from Panama City
10
Excellent
1 Reviews
5-Star Rating Recommendation
From
US $155Per Person
Reserve
Escape to San Blas All Inclusive and Visit 3 amazing places
Escape to San Blas All Inclusive and Visit 3 amazing places
10
Excellent
1 Reviews
5-Star Rating Recommendation
From
US $135Per Person
Reserve
Aroma Island San Blas 2-Day Package with Shared Cabin and Food
Aroma Island San Blas 2-Day Package with Shared Cabin and Food
10
Excellent
1 Reviews
5-Star Rating Recommendation
From
US $123Per Person
Reserve
Authentic San Blas Day Trip: Island Hopping & Community Visit
Authentic San Blas Day Trip: Island Hopping & Community Visit
9
Excellent
107 Reviews
5-Star Rating Recommendation
From
US $125Per Person
Reserve
San Blas Day Trip Cayos Limones, Perro Grande and Natural Pool
San Blas Day Trip Cayos Limones, Perro Grande and Natural Pool
9
Excellent
51 Reviews
5-Star Rating Recommendation
From
US $125Per Person
Reserve
San Blas Island-Hopping : Full-Day Adventure from Panama City
San Blas Island-Hopping : Full-Day Adventure from Panama City
9
Excellent
39 Reviews
5-Star Rating Recommendation
From
US $120Per Person
Reserve
San Blas Islands Small-Group Sailboat Cruise with Snorkeling
San Blas Islands Small-Group Sailboat Cruise with Snorkeling
9
Excellent
16 Reviews
5-Star Rating Recommendation
From
US $240Per Person
Reserve
Embera Village Private 2-Day Tour from Panama City
Embera Village Private 2-Day Tour from Panama City
9
Excellent
15 Reviews
5-Star Rating Recommendation
From
US $430Per Person
Reserve
San Blas Island Day Trip – Explore 4 Unique Island Attractions
San Blas Island Day Trip – Explore 4 Unique Island Attractions
9
Excellent
14 Reviews
5-Star Rating Recommendation
From
US $120Per Person
Reserve
Mamey Island Tour in the Caribbean of Panama
Mamey Island Tour in the Caribbean of Panama
9
Excellent
7 Reviews
5-Star Rating Recommendation
From
US $99Per Person
Reserve
Find A Tour In Eastern Panama

Top sights in Eastern Panama

Discover the top sights in Eastern Panama, Panama, from lush rainforest canopies to historic towns, and let you find nearby Tours & Sightseeing experiences that align with your plans here, so you can book stays that put the region's highlights at your doorstep.

Isla Mamey
Cayos Holandeses
Portobelo National Park
Porvenir Museum
Museum
Museum of the Kuna Nation
Colon Free Zone
Blanca Beach
Soberania National Park
Darien National Park
Chagres National Park
Galeta Island Marine Education Center
Area Silvestre de Nargana
Chepo Youth Recreation Center
Mirador Peru
Safarick's Zoo
Chepo Regional Hospital
Fuerte San FerNonedo
Gatun Eco Adventures
Fuerte Santiago

From sightseeing to restaurants
there’s plenty of things to do in Eastern Panama

Whether you love exploring landmarks or tasting local cuisine, you’ll find endless adventures here.

Most popular tours in Eastern Panama

See all Tours in Eastern Panama
San Blas Islands Small-Group Day Tour From Panama City

San Blas Islands Small-Group Day Tour From Panama City

8
Excellent
92 Reviews
5-Star Rating Recommendation
From
US $83Per Person
Reserve
2 Nights in San Blas Islands All Included - Cabanas Over the water

2 Nights in San Blas Islands All Included - Cabanas Over the water

8
Excellent
15 Reviews
4-Star Rating Recommendation
From
US $399Per Person
Reserve
Full Day San Blas All Inclusive Islands + Lunch + Snorkeling

Full Day San Blas All Inclusive Islands + Lunch + Snorkeling

8
Excellent
8 Reviews
5-Star Rating Recommendation
From
US $170Per Person
Reserve
Full Day 4 Amazing Spots in San Blas Cultural and Beach

Full Day 4 Amazing Spots in San Blas Cultural and Beach

8
Excellent
8 Reviews
4-Star Rating Recommendation
From
US $99Per Person
Reserve
San Blas 4-Stop Island Hopping Experience

San Blas 4-Stop Island Hopping Experience

8
Excellent
8 Reviews
4-Star Rating Recommendation
From
US $99Per Person
Reserve
San Blas Islands 4D/3N Trip with Holandeses Cays & Boat Tour

San Blas Islands 4D/3N Trip with Holandeses Cays & Boat Tour

8
Excellent
7 Reviews
4-Star Rating Recommendation
From
US $469Per Person
Reserve
San Blas ALL INCLUSIVE Sailing Charter - 2 Day/2 Night

San Blas ALL INCLUSIVE Sailing Charter - 2 Day/2 Night

8
Excellent
4 Reviews
4-Star Rating Recommendation
From
US $559Per Person
Reserve
San Blas Isla Diablo 2D/1N Stay + Meals & Island Tour

San Blas Isla Diablo 2D/1N Stay + Meals & Island Tour

9
Excellent
2 Reviews
5-Star Rating Recommendation
From
US $135Per Person
Reserve
See all Tours in Eastern Panama

Other tours in Eastern Panama

San Blas Islands 3D/2N Overwater Cabin + Meals & Boat Tour
San Blas Islands 3D/2N Overwater Cabin + Meals & Boat Tour
10
Excellent
1 Reviews
5-Star Rating Recommendation
From
US $399Per Person
Reserve
Panama City San Blas Islands Camping With Meals & Transport
Panama City San Blas Islands Camping With Meals & Transport
10
Excellent
1 Reviews
5-Star Rating Recommendation
From
US $217Per Person
Reserve
2D/1N San Blas Paradise Island Stay + Boat Tour– Oceanfront Cabin
2D/1N San Blas Paradise Island Stay + Boat Tour– Oceanfront Cabin
10
Excellent
1 Reviews
5-Star Rating Recommendation
From
US $170Per Person
Reserve
Day Trip To The San Blas Islands In Panama - Visit 3 Attractions
Day Trip To The San Blas Islands In Panama - Visit 3 Attractions
9
Excellent
186 Reviews
5-Star Rating Recommendation
From
US $120Per Person
Reserve
Small-Group Day Tour with Lunch & Transfers, San Blas Islands
Small-Group Day Tour with Lunch & Transfers, San Blas Islands
9
Excellent
95 Reviews
5-Star Rating Recommendation
From
US $169Per Person
Reserve
Group Day Tour to San Blas Islands Including Snorkeling
Group Day Tour to San Blas Islands Including Snorkeling
9
Excellent
49 Reviews
5-Star Rating Recommendation
From
US $79Per Person
Reserve
San Blas Day Trip - Snorkeling & Island Hopping From Panama City
San Blas Day Trip - Snorkeling & Island Hopping From Panama City
9
Excellent
42 Reviews
5-Star Rating Recommendation
From
US $125Per Person
Reserve
Panama City, Panama Beach and Culture Tour in San Blas Islands
Panama City, Panama Beach and Culture Tour in San Blas Islands
9
Excellent
24 Reviews
5-Star Rating Recommendation
From
US $119Per Person
Reserve
2 DAYS 2 NIGHTS All-Inclusive San Blas Islands on SAILBOAT
2 DAYS 2 NIGHTS All-Inclusive San Blas Islands on SAILBOAT
9
Excellent
22 Reviews
5-Star Rating Recommendation
From
US $700Per Person
Reserve
Group Day Tour of San Blas Islands with Snorkeling and Lunch
Group Day Tour of San Blas Islands with Snorkeling and Lunch
9
Excellent
17 Reviews
5-Star Rating Recommendation
From
US $79Per Person
Reserve
San Blas Island Day Trip – Explore 4 Unique Island Attractions
San Blas Island Day Trip – Explore 4 Unique Island Attractions
9
Excellent
14 Reviews
5-Star Rating Recommendation
From
US $120Per Person
Reserve
4D/3N San Blas Paradise Island Stay + Meals + Tour - Private Room
4D/3N San Blas Paradise Island Stay + Meals + Tour - Private Room
9
Excellent
2 Reviews
5-Star Rating Recommendation
From
US $384Per Person
Reserve
Show all Tours in Eastern Panama

Top-rated places to stay near Eastern Panama

Discover top-rated places to stay near Eastern Panama, Panama, where curated stays pair with unforgettable Tours & Sightseeing experiences.

Eastern Panama
Eastern Panama179+ Properties
Show all properties
10.0
Exceptional
(31 Reviews)
BEACH FRONT HOUSE SURROUNDeD BY 2 PRIVATE BEACHES
1991 ft² 10 Guests 4 Bedrooms 2 Bathrooms
Ocean View Villa
  • Oceanfront
  • Fireplace/Heating
  • Ocean View
US $681/Night For 7 Nights US $4,767
View Deal
10.0
Exceptional
(8 Reviews)
Play to Live San Blas
37.67 ft² 4 Guests 2 Bedrooms 2 Bathrooms
Ocean View Boat Rental
  • Oceanfront
  • Fireplace/Heating
  • Ocean View
US $560/Night For 7 Nights US $3,920
View Deal
10.0
Exceptional
(1 Review)
Private Bedroom on Paradise San Blas Island
1 Bedroom 1 Bathroom
Couples Retreat House
  • Pool
  • Balcony/Terrace
  • Breakfast
US $183/Night For 7 Nights US $1,278
View Deal
10.0
Exceptional
(31 Reviews)
Caribbean Haven Of Nature 'Preci Beach'
2750 ft² 8 Guests 4 Bedrooms 4 Bathrooms
Ocean View House
  • Hot Tub
  • Fireplace/Heating
  • Pool
US $348/Night For 7 Nights US $2,436
View Deal
Show all properties

Know more about Eastern Panama

Policies vary by listing, so you should review the specific cancellation terms on the booking page. You’ll typically find deadlines for free cancellation or partial refunds, and any non-refundable fees. For peace of mind, consider choosing a listing with flexible terms and reach out to the host if you have questions before you finalize.
Many experiences are family-friendly, but age requirements and activities vary. Check the listing’s suitability notes and any age restrictions, then contact the host if you need accommodations or substitutions to fit your family.
Accessibility varies by experience. Review the listing for accessibility notes and contact the host to discuss specific needs or accommodations for your group while you’re in the region.
Weather can affect schedules, especially for outdoor adventures. Listings may offer rescheduling options or alternatives in the event of rain or heat. Check the policy on the listing and coordinate with the host if weather concerns arise.
Booking is done directly through the listing, where you can select dates, the number of guests, and any add-ons. Inclusions (such as transportation, meals, or guide Services) differ by experience, so read the listing details carefully and confirm exact inclusions with the host before payment.
Payment methods appear at checkout for each listing, and some experiences may request a deposit or full payment upfront. Review the listing’s payment terms and any cancellation goodwill terms before confirming your booking.
The required gear and what’s included are listed in the experience details. Typical items to bring include sunscreen, water, and comfortable footwear. If you’re unsure, ask the host about gear provision or optional rentals before your trip.
Private or customizable options are often available. Use the listing’s private-booking or contact-host feature to discuss your plans, group size, and any special arrangements you’d like for your time in this area.